Imaging the central conducting lymphatics: initial experience with dynamic MR lymphangiography
R Krishnamurthy, A Hernandez, S Kavuk, A Annam… - Radiology, 2015 - pubs.rsna.org
R Krishnamurthy, A Hernandez, S Kavuk, A Annam, S Pimpalwar
Radiology, 2015•pubs.rsna.orgPurpose To describe a dynamic magnetic resonance (MR) lymphangiography technique
after intranodal injection of gadolinium-based contrast agent and to assess its feasibility for
evaluation of the central conducting lymphatics (CCL) in patients with pathologic disorders
that involve the CCL. Materials and Methods A retrospective evaluation of experience with
the dynamic MR lymphangiographic technique in six consecutive patients was performed
after institutional review board approval. Written informed consent for the percutaneous …
after intranodal injection of gadolinium-based contrast agent and to assess its feasibility for
evaluation of the central conducting lymphatics (CCL) in patients with pathologic disorders
that involve the CCL. Materials and Methods A retrospective evaluation of experience with
the dynamic MR lymphangiographic technique in six consecutive patients was performed
after institutional review board approval. Written informed consent for the percutaneous …
Purpose
To describe a dynamic magnetic resonance (MR) lymphangiography technique after intranodal injection of gadolinium-based contrast agent and to assess its feasibility for evaluation of the central conducting lymphatics (CCL) in patients with pathologic disorders that involve the CCL.
Materials and Methods
A retrospective evaluation of experience with the dynamic MR lymphangiographic technique in six consecutive patients was performed after institutional review board approval. Written informed consent for the percutaneous procedure was obtained from the patient, parent, or the legally responsible guardian. The dynamic MR lymphangiographic technique involves ultrasonographically guided intranodal injection of gadolinium-based contrast material into the inguinal lymph nodes, combined with sequential imaging of the chest and abdomen with a three-dimensional sequence optimized for soft tissue with high spatial resolution that provides time-resolved imaging of lymphatic transit through the CCL. Qualitative assessment of the images was performed for reliability of CCL visualization and for associated findings that could explain the clinical symptoms, including lymphangiectasia, chylolymphatic reflux, and chylous leak.
Results
The procedure was technically successful in all six patients. The dynamic MR lymphangiographic findings confirmed the presence of normal CCL morphologic structure in two patients and provided a possible explanation for clinical manifestations in the remaining four patients. The dynamic MR lymphangiographic procedure led to a change in management in two patients, continuation of conservative treatment in three patients, and confirmation of an alternative nonlymphatic diagnosis in one patient. Image quality for visualization of the CCL was considered good in all cases by the two readers. There were no known adverse effects related to the procedure.
Conclusion
The dynamic MR lymphangiographic technique with intranodal injection of gadolinium-based contrast material is feasible and can provide useful information in a variety of lymphatic flow abnormalities involving the CCL.
© RSNA, 2014
Radiological Society of North America