Blood vessels supply tissues and organs with oxygen, nutrients, cellular, and humoral
factors, while lymphatic vessels regulate tissue fluid homeostasis, immune trafficking, and
dietary fat absorption. Understanding the mechanisms of vascular morphogenesis has
become a subject of intense clinical interest because of the close association of both types
of vessels with pathogenesis of a broad spectrum of human diseases. The zebrafish
provides a powerful animal model to study vascular morphogenesis because of their small …