[PDF][PDF] Beneficial and rapid effect of infliximab on the course of toxic epidermal necrolysis

A Wojtkiewicz, M Wysocki, J Fortuna… - Acta dermato …, 2008 - pdfs.semanticscholar.org
A Wojtkiewicz, M Wysocki, J Fortuna, M Chrupek, M Matczuk, A Koltan
Acta dermato-venereologica, 2008pdfs.semanticscholar.org
Beneficial and Rapid Effect of Infliximab on the Course of Toxic Epidermal Necrolysis Page 1
© 2008 Acta Dermato-Venereologica. ISSN 0001-5555 doi: 10.2340/00015555-0462 Acta
Derm Venereol 88 420 Letters to the Editor Sir, Toxic epidermal necrolysis (TEN) is a life-threatening
dermatosis characterized by widespread detachment of the epidermis and mucosal erosions.
Depending on the area of skin affected, case fatality rates vary from 20% to 60% (1, 2). The
main causes of fatality are secondary infections caused by damage to the epidermis and …
DISCUSSION
At present there is no “gold standard” for TEN therapy (3). The reasons for this are that the pathogenesis is not entirely clear, and only a small number of patients is
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