Smoking while pregnant: Transplacental mutagenesis of the fetus by tobacco smoke
DM DeMarini, RJ Preston - JAMA, 2005 - jamanetwork.com
THE INTERNATIONAL AGENCY FOR RESEARCH ON CAN-cer (IARC) has identified
tobacco smoking as the cause of cancer at more organ sites (11) than any other human
carcinogen. 1 Eight of these organ sites have been examined for smoking-associated
genotoxic effects, and such effects have been found in all 8 sites. 2 The sites are the
oral/nasal cavity, esophagus, pharynx/larynx, lung, pancreas, myeloid organs,
bladder/ureter, and uterine cervix. To this long list of organs in adults in which tobacco …
tobacco smoking as the cause of cancer at more organ sites (11) than any other human
carcinogen. 1 Eight of these organ sites have been examined for smoking-associated
genotoxic effects, and such effects have been found in all 8 sites. 2 The sites are the
oral/nasal cavity, esophagus, pharynx/larynx, lung, pancreas, myeloid organs,
bladder/ureter, and uterine cervix. To this long list of organs in adults in which tobacco …