[HTML][HTML] SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles
P Déléris, D Bacqueville, S Gayral, L Carrez… - Journal of Biological …, 2003 - ASBMB
Recently, the control of phosphatidylinositol 3, 4, 5-trisphosphate (PtdIns (3, 4, 5) P 3)-
dependant signaling by phosphatases has emerged, but there is a shortage of information
on intranuclear PtdIns (3, 4, 5) P 3 phosphatases. Therefore, we investigated the
dephosphorylation of [32 P] PtdIns (3, 4, 5) P 3 specifically labeled on the D-3 position of the
inositol ring in membrane-free nuclei isolated from pig aorta vascular smooth muscle cells
(VSMCs). In vitro PtdIns (3, 4, 5) P 3 phosphatase assays revealed the production of both [32 …
dependant signaling by phosphatases has emerged, but there is a shortage of information
on intranuclear PtdIns (3, 4, 5) P 3 phosphatases. Therefore, we investigated the
dephosphorylation of [32 P] PtdIns (3, 4, 5) P 3 specifically labeled on the D-3 position of the
inositol ring in membrane-free nuclei isolated from pig aorta vascular smooth muscle cells
(VSMCs). In vitro PtdIns (3, 4, 5) P 3 phosphatase assays revealed the production of both [32 …