Publisher Summary Early studies pointed to the directions for subsequent investigations and
there has been continuing identification of other circulating autoantibodies, characterization
of their respective cellular antigens, and demonstration of the relationship between
autoantibodies and clinical syndromes. The antibodies identified in these studies have been
used extensively by investigators in molecular and cell biology as powerful probes for
understanding the precursor messenger RNA (mRNA) splicing. Autoantibodies designated …